Development of Anti-Virulence Therapeutics against Mono-ADP-Ribosyltransferase Toxins
Mono-ADP-ribosyltransferase toxins are often key virulence factors produced by pathogenic bacteria as tools to compromise the Sleep Bottoms target host cell.These toxins are enzymes that use host cellular NAD+ as the substrate to modify a critical macromolecule target in the host cell machinery.This post-translational modification of the target mac